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Intra-arterial Chemotherapy for Children With Retinoblastoma

Not yet recruiting
01/01/2011 to Present
10
Phase 1/Phase 2
Interventional

Conditions

Eligibility

0 - 10
No
Inclusion Criteria:
- Children with retinoblastoma in a single remaining eye with useful vision
Exclusion Criteria:
- None

Purpose


Interventions

  • Drug: Intra-arterial injection of melphalan
    Injection of 5 milligrams of melphalan into the ophthalmic artery once every 3 weeks for a total of 6 courses
  • Drug: Injection of melphalan into the ophthalmic artery
    Injection of 5 milligrams of melphalan into the ophthalmic artery in an eye affected by retinoblastoma

Outcome Measures

  • Salvage of eye and vision
    Three years from intervention
    Safety Issue: No

Contacts

Michael Weintraub, MD
michaelw@hadassah.org.il
Jacob Pe'er, MD

Locations

  • Hadassah University Hospital
    Jerusalem, 91120, Israel
    Recruiting

Sponsors

  • Hadassah Medical Organization
    Lead Sponsor
  • Israel: Ministry of Health

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