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Displaying 1 to 9 out of 9 total clinical trials for "embryonal rhabdomyosarcoma"

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  • Vincristine, Dactinomycin, and Cyclophosphamide in Treating Patients With Embryonal Rhabdomyosarcoma
    RATIONALE: Drugs used in chemotherapy, such as vincristine, dactinomycin, and cyclophosphamide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving vincristine, dacti...
    Status: Recruiting Phase 2 Location: Hyogo
  • Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Embryonal Rhabdomyosarcoma
    RATIONALE: Drugs used in chemotherapy, such as vincristine, dactinomycin, and cyclophosphamide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high energy x-rays to kill tumor cells. Giving more than one drug (combination chemotherapy) with radiation therapy may kill more tum...
    Status: Recruiting Phase 2 Location: Hyogo
  • Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Low-Risk Rhabdomyosarcoma
    RATIONALE: Drugs used in chemotherapy, such as vincristine, dactinomycin, and cyclophosphamide, work in different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy with radiation therapy may kill more tumor cells. It is not yet known which treatment regimen is more e...
    Status: Recruiting Phase 3 Location: North Carolina, Massachusetts, District of Colu...
  • Ixabepilone in Treating Young Patients With Refractory Solid Tumors
    RATIONALE: Drugs used in chemotherapy, such as ixabepilone, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. PURPOSE: This phase II trial is studying how well ixabepilone works in treating young patients with refractory solid tumors.
    Status: Completed Phase 2 Location: North Carolina, New York, Texas, Tennessee, Wis...
  • Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma
    RATIONALE: Drugs used in chemotherapy, such as vincristine, dactinomycin, cyclophosphamide, and irinotecan, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving combination chemotherapy together with radiation therapy may kill more tum...
    Status: Recruiting Phase 3 Location: North Carolina, Massachusetts, District of Colu...
  • Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma
    RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known whether chemotherapy is more effective with or without radiation therapy in treating patients who have rhabdomyosarcoma. PURPOSE: Phase III trial to compare the ef...
    Status: Completed Phase 3 Location: North Carolina, Mississippi, District of Columb...
  • Therapy to Treat Ewing's Sarcoma, Rhabdomyosarcoma or Neuroblastoma
    Background: - Pediatric solid tumors (Ewing's sarcoma, rhabdomyosarcoma, and neuroblastoma) are often difficult to cure with standard treatment. - Immune therapy using an experimental vaccine made from proteins from the patient's tumor cells may boost the body's immune response against the tumor. - The effects of chemotherapy on the immune sys...
    Status: Recruiting Phase 1/Phase 2 Location: Maryland
  • Combination Chemotherapy in Treating Patients With Previously Untreated Rhabdomyosarcoma
    RATIONALE: Drugs used in chemotherapy, such as dactinomycin, cyclophosphamide, vincristine, and topotecan, use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which combination chemotherapy regimen is more effective in treating rhabdomyosarcoma. PURPOSE: This randomized phase III trial is comparing two different combinat...
    Status: Completed Phase 3 Location: North Carolina, Mississippi, New York, California
  • Etiology Study of Kawasaki Disease
    The purpose of this study is to investigate the infectious etiology of Kawasaki disease (KD); a prospective household and case control study for Kawasaki disease will be done. The investigators will enroll Kawasaki disease cases who have at least five of the following manifestations: 1. fever for over 5 days 2. neck lymphadenopathy 3. lip fissure and...
    Status: Recruiting

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    There are three study types available to search on:

    • Interventional studies test specific treatments, procedures, devices, or behavioral changes.
    • Observational studies do NOT test for specific treatments or other changes. These studies measure health outcomes are studied in a specific group of individuals.
    • Expanded Access Records are not studies, they describe experimental treatments for patients who are not eligible to participate in clinical trials and are not responding to regular treatments. All experimental treatment use outside of clinical trials is documented in these records. Participants must be recommended by their provider to be eligible for expanded access to experimental treatment.
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    • Most clinical trials are designated as phase I, II, III, or IV (based on the FDA Regulations):
    • Phase I - Researchers test a new drug or treatment for the first in a small group of people (20-80) to evaluate its safety, determine a safe dosage range, and identify side effects.
    • Phase II - The study drug or treatment is given to a larger group of people (100-300) to determine if it is effective and to further evaluate its safety.
    • Phase III - The study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
    • Phase IV - The study drug or treatment is monitored after approval by the FDA to learn additional information including the drug's risks, benefits, and optimal use.
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    Outcome measures are used to evaluate trial results. For example, an obesity treatment might be evaluated by a measure of weight loss after 6 months. Measures can also be used to track side effects, such as number of heart attacks or mortality rate.

    (examples: response to drug or reduced mortality)
  • (examples: NIH or Merck)
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