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Subjects who have a clinical history of perennial rhinitis symptoms associated with dust
exposure or not associated with other perennial allergens, will have a positive challenge
with Dermatophagoides pteronyssinus. Subjects will be ppt negative and intradermal skin
test positive to Dust p Challenges will be performed with placebo or Dp extract three times
daily each f...
Location: Usf Asthma Allergy and Immunology Cru
Status: Recruiting
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Graves' disease is characterized by thyrotoxicosis, goiter, ophthalmopathy and dermopathy.
Pathogenesis involves autoimmune process. The investigators think temperatures of the area
involved in the inflammation may change. Thus the investigators plan to take temperature
pictures of Graves' patients using digital infrared thermal imaging system and observe the
change.
Location: National Taiwan University
Status: Recruiting
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Background:
- Patients who have advanced thyroid cancer have a low long-term survival rate. These
types of thyroid cancer do not respond well to conventional surgery or radiation, or to
specific thyroid cancer treatments such as radioactive iodine treatment and thyroid
hormone for thyroid stimulating hormone (TSH) suppression.
- Valproic acid...
Location: National Institutes of Health Clinical Center, ...
Status: Recruiting
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Background:
- In human DNA, the Fragile X (FMR1) gene helps to regulate the nervous and reproductive
systems. If the gene is abnormal, it can cause different kinds of problems, such as
abnormal menstrual periods, decreased fertility, muscle tremors, and mental
retardation. An abnormal FMR1 gene can also make a person more susceptible to other
...
Location: National Institutes of Health Clinical Center, ...
Status: Recruiting
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Graves thyrotoxicosis is a common autoimmune disease. Patients suffer at diagnosis from
weight loss, increased heart rate and stress intolerance. Some patients have difficulties in
regaining quality of life. Diagnosis is found through elevated thyroid hormones thyroxin,
suppressed TSH from the pituitary and elevated stimulatory antibodies, TRAb to the thyroid.
Selenium i...
Location: Jan Calissendorff, Medical clinic, Eskilstuna, ...
Status: Recruiting
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Currently there are few therapeutic options for the treatment of lid retraction secondary to
thyroid orbitopathy (TO) during the active stages of the disease. BoTox injection is
capable of creating a ptosis, that in the setting of TO can return the upper lid to a more
physiologic position, thus improving cosmesis, corneal lubrication and potentially quiescent
stage lid ...
Location: Mount Sinai Hospital
Status: Not yet recruiting
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The last two decades have witnessed an explosion of new research documenting the deleterious
impact that thyroid disease has on pregnancy and the postpartum period, in relation to
miscarriage preterm delivery intelligence quotient of the unborn child and health of the
mother postpartum. Both subclinical hypothyroidism and thyroid antibody positivity in
euthyroid women ha...
Location: Johns Hopkins University
Status: Not yet recruiting
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The purpose of this study is to investigate tocilizumab administration in patients with
moderately to severely or sight-threatening GO (Graves' ophthalmopathy) without response to
treatment with corticoid pulses. Currently these patients only have surgery as therapeutic
alternative.
The principal aim of this study is evaluate the efficacy and safety of tocilizumab treat...
Location: Hospital Clínico de Santiago
Status: Not yet recruiting
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Patients with hyperthyroidism and/or goiter are evaluated with blood samples and scintiscan
before they are treated with radioiodine for their thyroid disease. Because the
investigators do not get a histologically/final diagnosis the investigators want to make
sure, that the patients treated do not have a thyroid cancer when treated.
The investigators have found that th...
Location: herlev Hospital
Status: Completed
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Thyroid cancer is a relatively rare disease but its incidence is increasing in many
countries.. Early and accurate diagnosis leading to earlier treatment and intervention is
recognised as a major factor in determining a good outcomes. This study will investigate
new ways of diagnosing thyroid cancer from blood samples using proteomic and genetic
markers. The study will ...
Location: Sir Bobby Robson Cancer Researhc Unit
Status: Recruiting
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