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The current research program aims to study how sleep disordered breathing, age and genetics
affect memory in older adult veterans with Posttraumatic Stress Disorder (PTSD).
The study will help researchers and clinicians better understand the relationship among
PTSD, sleep disordered breathing, genetics and memory function.
Location: VA Palo Alto Health Care System
Status: Recruiting
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Fibromyalgia syndrome (FMS) is characterized by the presence of widespread pain, chronic
fatigue and typical sleep disturbances. The purpose of the current study is to investigate
the nature of sleep disturbance in FMS, using a novel technology. Peripheral arterial
tonometry is a method by which peripheral arterial tone is measured non - invasively using
in an ambulatory...
Location: Tel Aviv Sourasky medical center
Status: Not yet recruiting
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The study aims to observe the short term effect (3-month) of sleep disordered breathing
(SDB) on cardiovascular parameters, heart rate variability, endothelial function and
surrogate markers of atherosclerosis after acute cerebrovascular events (ACE). The long-term
effect (6-24-month) of Continuous Positive Airway Pressure (CPAP) on clinical vascular
outcome, cardiovascu...
Location: Inselspital
Status: Recruiting
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The aim of this placebo-controlled randomized study was to evaluate the efficacy of
Circadin™ 2 mg in improving total night sleep duration and stabilizing the circadian clock
phase in totally blind subjects with non-24 hour sleep-wake disorder.
Location: Sleep Disorders Center of Atlanta
Status: Completed
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The purpose of the study is to investigate the prevalence, clinical predictors and
consequences (effect on survival, chronic rejection) of sleep disordered breathing in lung
transplant recipients.
Location: Katholieke Universiteit Leuven
Status: Recruiting
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Endothelial dysfunction, or abnormal functioning of the lining of blood vessels, appears to
be a key process in the development of cardiovascular disease. Endothelial dysfunction
appears to be caused by both sleep disordered breathing and obesity. As endothelial
dysfunction is among the first clinical marker that predicts future cardiovascular events,
understanding molec...
Location: Mayo Clinic in Rochester
Status: Enrolling by invitation
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Oral appliances, such as Mandibular Repositioning Appliances (MRA), have emerged as a
treatment option for sleep-disordered breathing (SDB).
The purpose of this study is to compare active measurement of MRA compliance with patient's
self-report.
Location: Antwerp University Hospital
Status: Recruiting
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This study will assess the occurrence of multiple symptoms in cancer patients of 5 German
university hospitals. Primary goal of the study is to assess the prevalence of multiple
symptoms and related symptom clusters (e.g. pain, fatigue and sleep disorder).
Location: Department for Health and Nursing Science, Medi...
Status: Enrolling by invitation
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Our goals are to demonstrate an active leukotrienes (LTs) mediated inflammatory response is
involved in pathophysiology of sleep-disordered breathing (SDB), and to provide a
theoretical evidence for LTs modify therapy in treating pediatric patients with SDB.
The investigators have hypothesized that the pathophysiology of pediatric SDB involves
specific systemic and loca...
Location: Beijing Children's Hospital
Status: Enrolling by invitation
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The study hypothesis is that some children with Attention-Deficit-Hyperactivity-Disorder
(ADHD) who also have sleep onset difficulties will improve with Melatonin treatment to an
extent similar to that of stimulants treatment.
In order to check this hypothesis children with a new ADHD diagnosis who also have sleep
difficulties will be treated with either Melatonin or wi...
Location: Assaf Haroffeh Medical Center
Status: Recruiting
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