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Cervical cancer screening is a worldwide problem especially in the developing world of which
Tanzania belongs. It is diagnosed late in the third world because there are no diagnostic
facilities and resource people. It occurs in the age groups between 40 and above and
therefore affects the productive age of the community. It is well known that women
generally are the b...
Location: Kilimanjaro Christian Medical Center
Status: Not yet recruiting
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Chemoradiotherapy has become the standard of care for women with locally advanced cervical
cancer. The available data support a 30 to 50% reduction in the risk of death from cervical
cancer for women with locally advanced disease undergoing radiotherapy (RT) and concomitant
cisplatin-based chemotherapy compared to RT alone. Despite the fact that this is currently
the bes...
Location: University Medical Center Groningen
Status: Recruiting
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RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in
chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells,
either by killing the cells or by stopping them from dividing. It is not yet known whether
giving radiation therapy together with chemotherapy is more effective than radiation therapy
alone in t...
Location: Blumenthal Cancer Center at Carolinas Medical C...
Status: Recruiting
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The purpose of this study is three-fold: 1) to examine the ability of the experimental drug
tariquidar to improve chemotherapy results by blocking a protein (P-glycoprotein) on some
cancer cells that acts to pump out cancer drugs; 2) examine how tariquidar interacts with
the cancer drug docetaxel; and 3) evaluate the effectiveness of combination treatment with
tariquidar...
Location: National Institutes of Health Clinical Center, ...
Status: Completed
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To increase early detection of cervical cancer by increasing the proportion of Appalachian
women, age 18 and older, who receive Pap smears at appropriate intervals and return for
follow-up care when necessary.
Location: The Ohio State University Comprehensive Cancer ...
Status: Completed
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Among the immune cell therapy, autologous adoptive immune cell therapy is a method to
transfer the immune cells derived from peripheral white blood cells and expanded and
stimulated with various cytokines and tumor specific antigens in cancer patients. Recently,
the low-dose radiation is known to increase the immune response in many human cancer
patients. In a clinical t...
Location: Sang-Young Ryu
Status: Not yet recruiting
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The aim of the study is to assess the distribution of the most frequent types of human
papillomavirus in African women diagnosed with invasive cervical cancer.
Location: GSK Investigational Site
Status: Completed
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RATIONALE: Drugs used in chemotherapy, such as carboplatin and paclitaxel, work in different
ways to stop the growth of tumor cells, either by killing the cells or by stopping them from
dividing. Cediranib maleate may stop the growth of tumor cells by blocking some of the
enzymes needed for cell growth and by blocking blood flow to the tumor. It is not yet known
whether ...
Location: Leicester Royal Infirmary
Status: Recruiting
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RATIONALE: Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the
growth of tumor cells, either by killing the cells or by stopping them from dividing.
Radiation therapy uses high-energy x-rays to kill tumor cells. Specialized radiation therapy
that delivers a high dose of radiation directly to the tumor may kill more tumor cells and
cause less...
Location: Hammersmith Hospital
Status: Recruiting
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This proposal has been developed through collaboration between the University of Minnesota
and New American Community Services (NACS), and the research design is based on a needs
assessment conducted by the community partner. The investigators will test the hypotheses
that women who are offered home vaginal bio-specimen collection will have higher rate of
cervical cancer...
Location: Masonic Cancer Center, University of Minnesota
Status: Not yet recruiting
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