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Aug 23, 10 06:27AMThis study will determine the dose of sodium nitrite that can safely be used to prevent constriction, or tightening, of the arteries. Narrowed arteries in the brain can cause stroke. Animal studies show that nitrite injections improve blood flow and that injections over long periods of time prevent damage to the arteries in the brain; however, there is no information on ...Location: National Institutes of Health Clinical Center, ... Status: Completed» Read more
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Aug 23, 10 11:19AMMajor attempt is being given to the potential of curing patients with metastatic colorectal cancer due to the recognition of dramatic change in survival figures achieved in palliative chemotherapy combination treatment protocols. Achieving resectablity rates in previously unresectable patients has been defined as study endpoint among other well known primary and secondar...Location: Medical University Hospital Vienna Status: Recruiting» Read more
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Aug 23, 10 11:29AMRATIONALE: Giving chemotherapy drugs, such as fludarabine and cyclophosphamide, and total-body irradiation before a donor umbilical cord blood stem cell transplant helps stop the growth of cancer cells and prepares the patient's bone marrow for the stem cells. When the healthy stem cells from a donor are infused into the patient they may help the patient's bone marrow ma...Location: Masonic Cancer Center at University of Minnesota Status: Recruiting» Read more
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Aug 23, 10 12:10PMThe objective of this study is to compare the relative bioavailability of clarithromycin 500 mg tablets (Ranbaxy Laboratories Limited) with that of BIAXIN® 500 mg tablets in healthy, adult subjects under fasting conditions.Location: Gateway Medical Research Inc. Status: Completed» Read more
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Aug 23, 10 12:21PMAn open-label, multi-dose, single-arm, Phase 1 dose escalation study of XmAb®2513 will be conducted to define the MTD or recommended dose(s) for further study, to determine safety and tolerability, to characterize PK and immunogenicity, and to evaluate antitumor activity of XmAb2513 in patients with HL and ALCL (non-cutaneous) and who have received two or more prior ther...Location: Rush University Medical Center Status: Completed» Read more
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Aug 23, 10 01:56PMThe purpose of this study is to assess whether two higher doses (280mg or 420mg three times daily)of silymarin therapy are safe and tolerable, and shorten the illness in patients with acute viral hepatitis compared to placebo.Location: Tanta Fever Hospital Status: Recruiting» Read more
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Aug 23, 10 04:26PMThis study was conducted in order to evaluate the efficacy and safety of the cancer vaccine IMA901 and GM-CSF as adjuvant in the treatment of advanced renal cell carcinoma. Patients received vaccination with GM-CSF followed by IMA901 during the study period of 9 months. Patients received pre-treatment with a single i.v. infusion of cyclophosphamide prior to the first v...Location: Beatson Oncology Centre Status: Completed» Read more
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Aug 23, 10 06:35PMObjective: - To evaluate the antihypertensive efficacy of two brands of nifedipine 30mg in patients with hypertension. - To assess the safety of 8 weeks of therapy with two brands of nifedipine 30mg in patients with hypertension. - To study flow-mediated dilatation and oxidative stress in nonsmoker with essential hypertension but w...Location: Cardiovascular Division, Department of Internal... Status: Not yet recruiting» Read more
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Aug 23, 10 07:40PMDuring the past 15 years, however, the superior immunosuppressive efficacy of CsA and the well-known toxicity of long-term steroid therapy have prompted trials of steroid withdrawal from renal allograft recipients at various intervals after transplantation. Steroid withdrawal or avoidance must be balanced against the associated risk of precipitating acute allograft rejec...Location: Hospital "Ospedali Riuniti" of Bergamo Status: Completed» Read more
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Aug 23, 10 08:25PMThe objective of this study is to compare the relative bioavailability of fosinopril sodium 40 mg tablets (Ranbaxy Laboratories Limited, Lot No. 1238312) with that of Monopril® in healthy adult subjects under non-fasting conditions.Location: Gateway Medical Research Inc. Status: Completed» Read more
Hematology/Blood Disease
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