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Cardiac surgery relieves symptoms and increases life expectancy in cardiac patients, with
and without congenital heart disease (CHD). However, cardiac surgery involves many risks of
complications, such as bleeding, arrhythmias, and death.Right ventricular failure is another
complication, contributing to poor clinical outcome. Right ventricular failure is a clinical
syndr...
Location: Academic Medical Center
Status: Not yet recruiting
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In Canada, 218,000 units of fresh frozen plasma and frozen plasma were transfused in
2005.Cardiac surgery patients are the largest recipient group for FP transfusions. Despite
this, no studies have characterized the use of FP in relation to coagulation test
abnormalities or bleeding, or how these and other clinical determinants influence the
decision to transfuse FP. Fu...
Location: Ottawa Hospital
Status: Not yet recruiting
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Hypothesis of the study is that patients undergoing major cardiac surgery can develop
extracardiac complications correlated to cardiopulmonary by pass.
Location: Cardiac Intensive Care Unit, San Giovanni Batti...
Status: Recruiting
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The primary aim of our prospective, randomized, double-blind interventional clinical trial
is to determine the effectiveness of high dose atorvastatin therapy to reduce post operative
cognitive dysfunction (POCD) in patients undergoing cardiac valve surgery. We hypothesize
that therapy with high dose atorvastatin will significantly reduce the incidence and/or
severity of...
Location: Duke University Medical Center
Status: Not yet recruiting
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The purpose for the investigators study is to investigate the severity and incidence of
respiratory insufficiency using transcutaneous carbon dioxide (TcPCO2) monitoring as an
adjunct to the current standard of care for early detection of inadequate ventilation in
post-operative surgical in-patients undergoing cardiac surgery after discharge from
intensive care unit (ICU...
Location: Baylor University Medical Center
Status: Recruiting
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Patients with respiratory failure following cardiac surgery are randomized to receive
standard therapy versus non invasive ventilation. The hypothesis is that patients receiving
non invasive ventilation will perform better than those who received standard therapy.
Location: Ospedale San Raffaele di Milano, Italy
Status: Recruiting
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This study aims to identify genetic causes of adverse events after cardiac surgery, such as
atrial fibrillation, myocardial infarction and heart failure.
Patients undergoing heart surgery at Brigham and Women's Hospital and Texas Heart Institute
are eligible to participate
Location: Brigham and Women's Hospital
Status: Recruiting
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There are currently several schemes described for anticoagulation with heparin and its
reversal with protamine during cardiac surgery with CPB. The oldest, and most used in our
routine environment, is the scheme of fixed doses, in which a bolus dose of heparin at the
start of CPB is established in IU/kg of body weight and the dose of protamine at the end of
CPB is calcul...
Location: Instituto de Cardiologia do Rio Grande do Sul
Status: Completed
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One of the main problems that faces children undergoing congenital cardiac surgery is
posoperative pain management. PCAs (Patient Controlled Analgesia) and NCAs (Nurse Controlled
Analgesia) are the main means of pain management here at NCH. In this study, the
investigators will review the difference between different PCA and NCA modalities. Also, the
investigators aim to...
Location: Nationwide Children's Hospital
Status: Active, not recruiting
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The purpose of the study is to evaluate kidney biomarkers and determine if there is a
correlation between erythropoietin levels and acute kidney injury after cardiac surgery. An
early biomarker for kidney injury may be helpful in identifying, monitoring and managing
patients at risk for kidney failure after cardiac surgery. To evaluate EPO's role as a
predictor of poor...
Location: University of Michigan Hospital
Status: Recruiting
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