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Histiocytoid cardiomyopathy (OMIM #500000) is a rare genetic disorder that presents as arrhythmia or dilated cardiomyopathy, primarily in females less than two years of age. Histopathologically, nodul ar...
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…since pocketziggy’s last post, but for a good reason. Preparing for Anatomic and Clinical Pathology board examinations has taken a toll on pocketziggy’s professional and pers onal...
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Aside from the New Orleans Saints winning Super Bowl XLIV, not much happened over the week-end, so here’s a mini-lesson. Contrary to the general rule of thumb that derangements involving clottin g...
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I must say that intra-operative use of NovoSeven®RT has saved a few patients on my watch. The licensed indications include treatment of episodic bleeding in patients with congenital Factor VII def iciency...
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A weary pathology resident was called one evening and was requested to calculate the dose of 25% human albumin for a 100 kilogram patient with ascites scheduled for a therapeutic tap. Her advice was t o...
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Hexosaminidase heterodimeric isozyme A, along with cofactor GM2 Activator Protein, catalyzes the degradation of GM2 gangliosides, and is composed of subunits encoded by the HEXA and HEXB genes. Mutati ons...
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Pain at the transfusion site, when not associated with acute hemolytic transfusion reactions, is most commonly due to the release of bradykinin from venule endothelium, and it is also possibly potassi um...
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Big news for us today! After review, pocketziggy has been added to the Medpedia News & Analysis – Medical Specialties channel at the Medpedia Project website. This means that you can read ou r...
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A 14 year old female with Trisomy 21 and a new diagnosis of Pre-B ALL is undergoing induction using a modified COG protocol, and is receiving asparaginase (Elspar) to deprive the leukemic cells of ess ential...
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Got a call from an intern covering our local Veteran’s Hospital regarding a male inpatient who had thoracentesis performed earlier in the day and now was bleeding into his thoracic cavity. He is on...
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