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Has anyone with COPD been intolerant of inhalers and what did they do?

I have COPD and have been on all kinds of inhalers and nebulizers for years and now find that I cannot tolerate them anymore! Has anyone gone through this and what did they do? Did they find a substitute? I'm also on oxygen since my problem in the last few months. I've just had a bronchoscopy which turned out fine.
Female
Female
asked Jul 17, 2010 at 06:31PM in Asthma
7 Answers
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  • 1
    Votes
    answered Jul 19, 2010 at 07:13AM
    May I ask what the names of the medications were, and what kind of negative side effects you suffered from them?
  • 1
    Votes
    answered Jul 19, 2010 at 07:22AM
    Intollerant generally means that you are having side effects. Do you mean you are intollerant, or that the meds aren't working anymore? If side effects, there may be a way to change medications or give you different formulations. Assuming you mean they are not working, this could be due to a worsening of your disease. As Stephen mentions above, would need to know what the medications you are taking/have taken, what if any side effects, and how these medications are delivered, i.e. inhaler, nebulizer, etc.
  • 1
    Votes
    answered Jul 19, 2010 at 07:54AM
    A few people appear to react badly to the propellants in the new MDI inhalers which have had to change from CFC propellants to HFA propellants. If so, have you tried dry powder inhalers such as used for Foradil aerolizer, Advair discus or Symbicort Turbuhaler?
  • 1
    Votes
    answered Jul 20, 2010 at 02:02PM
    If you're taking several medications simultaneously, it could be that just ONE is causing the problem and changing medications may help the issues you're experiencing.

    Another thought would be to consider if you have ever had issues with dairy. Most, if not all dry-powder inhalers contain lactose as a carrier which could pose some potential issues if you're sensitive to it (http://aaia.ca/en/milk_proteins_and_allergy_medications.htm). I've also heard of the same phenomenon about people reacting adversely to pressurized metered dose inhaler propellants as Chris mentioned above.
  • 1
    Votes
    answered Jul 20, 2010 at 06:14PM
    Thank you Kerri M

    Yes, I do take lactaid for dairy products !

    By taking all those Meds I listed , it 's been over the years and when one didn't work then the Dr would perscribe another-------I've always had good luck but then all of a sudden, in Feb., I started getting that reaction and then after that, with each one I tried I'd get the same reaction

    Again, thank you and I will check with my Dr about the Dairy products.
  • 0
    Votes
    answered Jul 20, 2010 at 06:16PM
    Thank you so very much for answering my question !!

    I should have mentioned I also have Asthma

    I have taken just about everything, I was on Symbacort for at least 2 years and it was working really well and then around last Feb., it was making me very breathless, so much so that it "put me down" for most of the day---by that, I mean I couldn't get off the couch. I have been on Advair, Duo Neb Nebulizer for at least 6 years , Spiriva,Atrovent, combivent, albuterol with no problem with any of these until last Feb. while taking Symbicort!! That's where it all started and then I was unable to take Advair, Spiriva. Pulmacort, Duo Neb

    My reaction is that I cannot breath any medication deeply because it gives the same reaction as I mentioned. I did go to Mayo clinic and they said they too had never heard of anything like this and thought that it is "fear" which it definitely is not !! I think they may have misunderstood me thinking I said my throat 'closes' when I inhale--and it doesn't close!! it's just that if I get the least little bit too much, my breathing becomes very hard ! They also suggested going to an ENT-- that it may be my vocal cords not reacting right when I inhale which is why the Pulmanogist gave my a Bronchoscopy and included a vocal cord exam. Everything turned out fine

    I am also, right now, on a treatment of Prednisone, that I'm hope and praying to get off because for the last 3 years, I've been on 5mg per day for RA . What is keeping me going is that I'm using a spacer on my Duo Neb and I can get a little more med. doing it that way but certainly not even 98% of the dosage-----but it keeps my airways open longer--- for awhile

    I have not taken Symbicort Turbuhaler nor Foradil aerolizer . Is the aerolizer the same as a Nebulizer?

    I am beginning to wonder if my other meds could have some effect ie; Coreg. norvasc, plaquenil,.prednisone, tylonel arthritis. aspirin. simvastatin, Vit D 50000 iu one per week because my internest took me off Lisinopril because it was making me cough a lot , hence, I'm allergic to ace inhibiters

    I hope I didn't confuse you too much with all this info and I really hope you'll be able to help me or make any suggestions?

    Again, thank you sooo very much!!!
  • 1
    Votes
    answered Jul 20, 2010 at 06:57PM
    Aspirin and other NSAIDs can also be asthma triggers in some (but certainly not all) people. The Foradil aerolizer is another dry powder inhaler containing formoterol, the same bronchodilator component of Symbicort [but without the inhaled steroid component of Symbicort (budesonide)].

    I've also heard that prednisone contains trace amounts of lactose, so that's something else to mention that to your doctor [but of course, don't quit these meds on your own!]

    Depending on where you live, Symbicort also comes in MDI ("regular" inhaler) in the United States, and the lower strengths of Advair [250/50 and 125/25] are also available in MDI, which do not contain lactose.
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