answered Jul 20, 2010 at 08:31PM
Classically, the thumb was not considered a good site, but the reasons have to do with ancient blood glucose testing. Back when lancets were 21 gauge and blood drop size was 10-15 uL, there was substantial residual pain at the lancing site. If you touched the area over the 3-4 hours after lancing, it really hurt.
With 33 gauge lancets, better lancing devices and small blood drops needed there is no reason not to use the thumb as a testing site.