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Can Hereditary Multiple Exostoses skip a generation?

My mother has HME (Hereditary Multiple Exostoses) and 5 of my brothers and sisters have it. It is an 8-person family, not all from the same father but I dont know if that matters because it was passed down through my mother. I am having a child and have finished growing without knowingly having it. Could my child have it?
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asked Jul 28, 2010 at 09:34PM in Other
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    answered Jul 29, 2010 at 12:52PM
    In families with multiple exostoses, affected patients are usually recognizable because they show short stature and bone deformities, however within a family with M:E: there might be patients who are very mildly affected and exostoses are few and small, and can be seen only after xays studies. Therefore I must say yes, you could have an affected child, but only if you have the abnormal gene, even if you have multiple exostoses in a very mild way, there would be a 50% risk for your chind to be affected. If you want to know for sure you should ask one of your affected siblings to have the genetic test performed. Once the gene involved in multiple exostoses in your family is recognized, you could have the test on yourself.
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