Cellulitis is an inflammatory reaction involving
the skin and underlying subcutaneous
tissue. Patients who undergo
surgery for breast cancer, whether in the
setting of breast conservation or mastectomy, are at
risk of developing infection at the surgical site and
in soft tissue. Surgical trauma predisposes patients
to skin infection by breaching normal tissue barriers.
The widespread use of antibiotic prophylaxis
has reduced, but not eliminated, infections associated
with surgical intervention. Postoperative skin
infections develop after 2%–7% of all surgical procedures;
there is, however, considerable variation
according to the type of surgery being performed,
the duration of the operation, and the presence of
comorbid illnesses.1 The incidence of surgical site
infections is 12.4% following mastectomy with immediate
implant reconstruction, 6.2% following
mastectomy with immediate reconstruction using
a transverse rectus abdominis myocutaneous
flap, and 4.4% following mastectomy only.2 The
reported incidence following breast-conserving
therapy ranges from 2.5% to 14%.
REF:
http://www.supportiveoncology.net/journal/articles/0705174.pdf