Medpedia

The content on or accessible through Medpedia.com is for informational purposes only. Medpedia is not a substitute for professional advice or expert medical services from a qualified health professional. Read more

Medpedia Answers

(Cardiology/Heart Disease)

Medpedia Answers is a platform for asking and answering questions about health and medicine. Read more.

What is an Alternative medication for high cholesterol

62 yr old, Female
62 yr old, Female
asked Sep 11, 2009 at 08:07PM in Cardiology/Heart Disease
10 Answers
10 Following
↓ answer this question
Sort By Date Votes
  • 1
    Votes
    answered Sep 11, 2009 at 08:31PM
    Tell me what you are taking and I will give you an alternative.
    If you mean alternative as in herb, vitamin or some other natural substance, give me more details about how high your numbers are and reasons you are looking for an "alternative".
  • 1
    Votes
    answered Sep 24, 2009 at 10:39PM
    There are many alternatives to manage High cholesterol. Nobody gets high cholesterol overnight. The first line of mamgement should be lifestyle changes including dietary approaches. Cholesterol is the result of an ongoing systemic inflammation in the body,many a times because of unhealthy lifestyle and eating habits. There are minority of people who get it as part of their heridity.

    There are a strong link to the inflammation and what one eats. So go for healthy diet first.

    The whole concept of total cholesterol, high LDL may change in coming years as there are lots of research happening in this field.
    • Thank you, Manoj
      Gina Pera commented Apr 08, 2010 at 11:20AM
  • 1
    Votes
    answered Oct 10, 2009 at 08:08AM
    My skeptical self agrees with Dr. Kumar, even though - like virtually all heart attack survivors, even those with normal cholesterol levels - I've been prescribed a daily statin since my heart attack last year.

    It's important to remember that the class of cholesterol drugs called statins have been a goldmine for pharmaceutical companies. Lipitor, for example, at $26 billion in annual global sales is the world's biggest selling drug produced by the world's biggest pharmaceutical company, Pfizer.

    Any drug that relatively young or middle-aged people can be convinced to take every day for the rest of their lives is very good for Big Pharma. Guidelines for treatment protocol are commonly written by doctors who have financial ties to the very drug companies who manufacture the drugs they are recommending. This type of blatant conflict of interest is a serious cause of concern for patients who are prescribed statins. Read more about Big Pharma marketing success at 'The Ethical Nag: Marketing Ethics for the Easily Swayed': http://www.ethicalnag.org

    What statin drugs do, without a doubt, is lower our LDL (bad) cholesterol numbers in a way that cannot be touched even by aggressive lifestyle changes in diet or exercise. But the question is: do we really need to lower those numbers? A number of studies have already questioned the commonly held link between high LDL cholesterol and cardiovascular mortality, particularly for women as we age. Yet drug companies have done a truly spectacular job in convincing both physicians (through industry-funded ghostwritten articles in medical journals) and patients (through those "Direct To Consumer" ads you've seen on TV and magazines) that we MUST control our cholesterol levels in order to protect our hearts.

    Stay tuned...
    • I agree with you, Carolyn. But we can't blame it all on pharma marketing. We must also look to the mindset of physicians who are looking for surefire ways to help their patients -- as well as the mindset of patients who are looking for ways to avoid hrad lifestyle changes or who, in the case of those with impulsive and other disorders, cannot adhere to healthier lifestyle habits.
      Gina Pera commented Apr 08, 2010 at 11:22AM
  • 0
    Votes
    answered Apr 07, 2010 at 07:47PM
    Leeper NJ, Ardehali R, deGoma EM, Heidenreich PA. Statin use in patients with extremely low low-density lipoprotein levels is associated with improved survival. Circulation. 2007;116:613-618.

    These investigators found that even low LDL less than 40 mg / dL was associated with survival and no greater side-effects. I'd still treat to the guidelines. It does not bother me that pharmaceutical companies make money off of these medications. They have to eat too.

    Sadly, so long as people must eat fast food then they must take statins.
  • 2
    Votes
    answered Apr 08, 2010 at 11:55AM
    You seek "alternative medication" for high cholesterol, but as Edmund Hayes point outs, you don't mention if you are seeking an alternative medication to the one you are currently taking or perhaps a "natural" alternative to medication.

    I will assume you are seeking a non-medication alternative for high cholesterol and other risk factors for cardiovascular disease. For that, consider the research implicating several vitamin and mineral deficiencies, many of which are been associated not only with high cholesterol but also with high blood pressure, diabetes, and other risk factors for cardiovascular disease.

    1. B vitamins.

    In particular, Niacin (also known as vitamin B-3) can increase HDL or "good" cholesterol levels. You can take a supplement or find it in dairy products, eggs, fowl, fish, lean meats, and nuts. While some sources recommend niacin in isolation, know that this can create a "niacin flush," which other sources say is ill-advised, especially in regard to organ damage. Note that the non-flush types of niacin apparently do not have the same effect on HDL.

    Folic acid (also a B vitamin) regulates homocysteine, a suspected marker for heart disease.

    Rather than taking individual B vitamins, however, the conservative recommendation is to take a full B-complex supplement, since the Bs work better in combination and several other Bs are important in lowering homocysteine; not just folic acid.

    2. Magnesium - Many studies have linked magnesium deficiency to high blood pressure, and some studies have linked magnesium supplementation to a decreased risk of death from heart disease. Magnesium is known as a natural calcium channel blocker. It balances excess calcium that can cause muscle spasms in the heart (a heart attack).

    Magnesium also may reduce the risk of developing type 2 diabetes. The American Heart Association names diabetes as a major risk factor for cardiovascular disease.

    Magnesium research scientist Mildred Seelig writes about magnesium and disease in her 1980 book MAGNESIUM DEFICIENCY IN THE PATHOGENESIS OF DISEASE: Early Roots of Cardiovascular, Skeletal. and Renal Abnormalities, Mildred S. Seelig, M.D., M.P.H., F.A.C.N.
    New York University Medical Center. It is available online here:

    http://www.mgwater.com/Seelig/Magnesium-Deficiency-in-the-Pathogenesis-of-Disease/chapter5.shtml

    You can learn more about magnesium's role in maintaining health and preventing disease at the website of the Nutritional Magnesium Association. This page lists several magnesium research studies:
    http://www.nutritionalmagnesium.org/index.php?page=Research+Studies

    I hope you find this information helpful.
  • 0
    Votes
    answered Apr 08, 2010 at 02:42PM
    I would add blueberries to the list of things to try out. Has worked very well for me since 2004 when I read about this USDA study showing blueberries lower cholesterol. How's that for alternative :-)

    http://www.news-medical.net/news/2004/08/23/4286.aspx
  • 0
    Votes
    answered Apr 08, 2010 at 11:17PM
    The global sales of Lipitor were only 12.5 billion dollars in 2009 and not 26 billion and these sales were declined by 1 billion dollars from the 2008 levels.

    Ref. http://knol.google.com/k/top-ten-twenty-best-selling-drugs-2009#

    It is easy to blame the industry which has discovered and developed so many life saving drugs and improved quality of life of million of patients. The sales of Lipitor brand will soon disappear as the product is going generic next year resulting in loss of 80-90% of the sales within a month after patent expiry.

    As far alternatives or natural treatment for statin like effects, there was intensive search for finding natural statin like compounds in plants without any success. There was a compound called Guggal from traditional indian System of Medicine " Ayurveda" which had shown some efficacy as a lipid lowering agent in some early clinical trials and was launched in India in early 90s. Several TCM products have failed in clinical trials.

    For official information

    The National Center for Complementary and Alternative Medicine (NCCAM) is the Federal Government's lead agency for scientific research on complementary and alternative medicine (CAM).

    http://nccam.nih.gov/
  • 1
    Votes
    answered Apr 09, 2010 at 09:05AM
    The first line therapy to improve your blood cholesterol profile would be to focus on lifestyle behaviors, particularity diet: more fresh (or frozen) vegetables and fruit, whole grains and heart-healthy fats from olive and canola oils, omega-3 rich fish at least 3x/week, nuts and nut butters, and avocado as well as one glass of red wine and avoidance of red meat, butter and anything containing transfat or saturated fat. And daily physical activity. These crucial lifestyle behaviors should be attempted for at least 4-6 months before medication is started and should be maintained even if a statin is deemed necessary later on. However, you might consider consulting a registered dietitian in your area who can pinpoint the specific areas of your diet that can be adjusted to give you the best cholesterol profile for you personally.
  • 0
    Votes
    answered Jan 02 at 09:15PM
    Look into Red rice yeast -- but please note that the FDA made RRY producers in the US take out one of the key components of it because this oriental fermentation product was competing with the emerging statin drug industry (against lovastatin I believe). In the US, you can't get RRY with the key active ingredient, however, I have learned there are other active parts of RRY that may be benefit for lowering cholesterol.

    You can get side effects from it even thought it's a natural supplement -- you should look into them. I have been told to watch your CoQ10 levels.

    Also, look into plant sterols -- these are options. I give these to my kids.

    You can read this article from Wash University St. Louis -- they are tops for cholesterol research:
    http://news.wustl.edu/news/Pages/6744.aspx.
  • 0
    Votes
    answered Jan 06 at 02:49PM
    Red Rice Yeast is just a natural statin and it has the same side effect profile as any prescription statin and must be used with understanding.
    Red Rice Yeast also is not controlled by the FDA and its purity is subject to question. There have been many reports of companies "spiking" their Red Rice Yeast products with actual statins. There are also many reports showing how the concentration of the active ingredient varied widely from batch to batch. Lastly there are many reports about the contamination of the products with undesirable and sometimes toxic ingredients.
    I would NEVER recommend this product.
    If you are going to take a statin drug (remember Red Rice Yeast is a statin), you might as well take a prescription statin that is standardized and has some level of quality control built into the manufacturing process.
    • Edmund:

      I don't see why you would never recommend this product, especially under the right circumstances with a doctor's supervision and of course the right type of vetted supplier. Many people have side effects to statins or they won't take prescription drugs.

      The question said "alternative" medication which I read as something natural or a non pharmaceutical.

      This is a very interesting article about RRY:
      http://www.drweil.com/drw/u/QAA400589/Red-Rice-Yeast-Instead-of-Statins.html

      There are more articles coming out showing that there are other components in RRY that have a lipid loweri
      Chris Hempel commented Jan 08 at 03:43PM
    • There are NO circumstances when anyone should use a product that is not regulated and when its potency is not necessarily standardized.
      RRY is a statin, that all there is 2 it.
      If you are going to use a statin, you should use one that has a strength that you can count on.
      If you have side effects from statins, guess what, you will have the same side effects from RRY!
      Natural products are great but some are not.
      Poison Ivy is natural and I don't think anyone would think of eating that.
      Asbestos is also natural, so is arsenic, so is radiation but common sense tells us to stay away from them.
      Edmund M Hayes Pharm.D. commented Jan 08 at 04:15PM
    • Edmund:

      There is no point in arguing about this because I agree with you on many levels, including that statins should be tried first for cholesterol issues and have been proven to be very safe.

      There are doctors that do recommended it in some cases for their patients: http://www.npr.org/templates/story/story.php?storyId=92103272

      The question seemed to lead to "alternatives" -- most people know that statins are the standard treatment. I would have just told this poster to look at statins but it seemed like they were looking for a natural substance.

      If we assume this person is looking for s
      Chris Hempel commented Jan 08 at 05:38PM
    • Edmund:

      There is no point in arguing about this because I agree with you on many levels, including that statins should be tried first for cholesterol issues and have been proven to be very safe.

      There are doctors that do recommended it in some cases for their patients: http://www.npr.org/templates/story/story.php?storyId=92103272

      The question seemed to lead to "alternatives" -- most people know that statins are the standard treatment. I would have just told this poster to look at statins but it seemed like they were looking for a natural substance.

      If we assume this person is looking for s
      Chris Hempel commented Jan 08 at 05:39PM
    • btw - I am not a big fan of statins but they do work.
      There is a great website about some of the bad things about statins.
      http://www.spacedoc.com/
      A bit nutty but he makes some good points.
      Edmund M Hayes Pharm.D. commented Jan 08 at 06:06PM
The content on or accessible through Medpedia.com is for informational purposes only. Medpedia is not a substitute for professional advice or expert medical services from a qualified health professional. Read more
Editor Directory - browse by last initial
ABCDEFGHIJKLMNOPQRSTUVWXYZ
Professional Directory - browse by last initial
ABCDEFGHIJKLMNOPQRSTUVWXYZ
Cancel