answered Mar 18, 2011 at 06:15PM
For severe refractory cases, it is usually best to provide an extended course of vancomycin with a taper at the end. Though not necessarily supported by data, I also tend to give people probiotics such as lactobacillus acidophilus, and/or have them eat yogurt. If that doesn't work, there appears to be some good data behind fecal transplants, although I have not seen it done personally.