answered May 19, 2011 at 03:42PM
Type 2 diabetics frequently (but not universally) require much higher doses of insulin because their problem is caused by insulin resistance.
A usual starting dose for type 1 diabetics is 1/2 unit/kg per day, split half between long acting (basal) and short acting (bolus) insulin. For a 70 kg person, 35 units a day would therefore be reasonable starting total dose (although titration will need to happen, as mentioned above).
A type 2 diabetic may be maintained on oral agents such as metformin and have a long acting agent added (if fasting glucoses are elevated), or short acting added if glucoses are elevated during meals. Some very resistant type 2 diabetics require 100 units or more of insulin per day, while others require far less.
Insulin therapy is very personalized because people require very different amounts.