Hi Lisa,
I wish I knew. I've long noticed the correlation but could not find a study or any evidence to back it up.
I know that magnesium deficiency can sometimes exacerbate allergies, and there is limited study showing magnesium deficiency in some populations of people with ADHD. We know for sure that most Americans are deficient in magnesium, though. And this is no doubt worse for those who take calcium supplements without magnesium. I'm guessing it's worse for kids who drink a lot of milk.
Magnesium is a critical element to healthy functioning in the brain and the rest of the body. It has a sort of push-me/pull-you relationship with calcium. Simply put, calcium gives rigidity and structure to muscles, tendons, and cells, whereas magnesium gives flexibility. Calcium stiffens and magnesium relaxes, in other words.
Magnesium is also a precursor, or building block, to norepinephrine, a brain chemical often targeted with ADHD medication treatments.
So, magnesium is one issue. I've become known as the "mag nag" in our local Adult ADHD discussion group, because it can help with so many of the physical complaints that people have -- stiff neck, stiff back, hypertension, allergies, restless legs syndrome, migraines, constipation, etc. Dr. Carolyn Deane wrote an excellent mainstream book (with a regrettably hokey title) called "The Miracle of Magnesium." You can read that for more info.
My husband, who has ADHD, has been helped immensely by mag supplementation -- less acute allergies during pollen season, no more "startle response," etc. One of my friends who has ADHD finally relented to my nagging and tried it. He said that the ball of his anxiety in the pit of his stomach -- present for 20 years -- finally went away with magnesium. So, maybe it's not too hokey to call it a miracle. ;-)
There's a product called CALM that's available online. There are various versions, some with calcium. The thinking is, if one is deficient in magnesium, one should forgo supplementation with calcium until the mag is built up. So, I'd go with the straight mag if you're going to try it.
Beyond magnesium, Dr. Charles Parker emphasizes the importance of screening for food allergies among people who present with ADHD-like symptoms. He's an expert on Medpedia. And you can check his excellent blog at
http://www.corepsychblog.com
Back to your original question about Vyvanse.....you can search Dr. parker's site for great info on Vyvanse titration, etc.
I hope that helps.
Gina Pera, author
Is It You, Me, or Adult A.D.D.?