Central anticholinergic syndrome has been described as a response that occurs after receiving propofol, as well as other drugs with direct or indirect cholinergic or anticholinergic action. The syndrome causes impairment in central cholinergic transmissions to the cerebral cortex. Clinical symptoms can range from depressed neurological states, such as decreased level of consciousness, stupor, amnesia and coma to hyperactive states including restlessness, anxiety, logorrhea, agitation and seizures. Other effects associated with this syndrome can include: headache, disorientation, delirium, shivering, dysarthria, and HYPERTHERMIA with temperatures reported as high as 41.5 degrees Celsius.