Medpedia

Rajappa S Kenchappa PhD

Associate Professor, Blanchette Rockefeller Neurosciences Institute

Morgantown, WV

Education

Universities

National Brain Research Centre, India

PhD, Neuroscience

Mysore University, India

MSc, Biochemistry

Mysore University, India

BSc, Chemistry and Biology

Mentors

Professor. Bruce D Carter

Vanderbilt University Medical School Nashville, TN

Professor. Vijayalakshmi Ravindranath

Founder Director, National Brain Research Centre and Chairman, Centre For Neuroscience, Indian Institute Of Science, Bangalore

Experience

Associate Professor

Blanchette Rockefeller Neurosciences Institute
2010 to present

Research Instructor

Vanderbilt University Medical School
2006 to 2010

Postdoctoral Fellow

Vanderbilt University Medical School
2004 to 2006

Project Scientist

National Brain Research Centre, India
2002 to 2004

Memberships

Member

Society for Neuroscience
2006

Publications

Articles

"Mutation analysis of HIF-prolylhydroxylases (PHD/EGLN) in individuals with features of phaeochromocytoma and renal cell carcinoma susceptibility."

Endocrine-related cancer
Vol. 18 - 1 2011; 73-83
PubMed ID: 20959442

"P75NTR mediated apoptosis in sympathetic neurons involves a biphasic activation of JNK and up regulation of TACE/ADAM17."

The Journal of biological chemistry
2010;
PubMed ID: 20421303

"Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers."

Neuron
Vol. 62 - 2009;
PubMed ID: 19376068

"NRIF is a regulator of neuronal cholesterol biosynthesis genes."

Journal of molecular neuroscience : MN
Vol. 38 - 2009;
PubMed ID: 18677445

"Ligand-independent signaling by disulfide-crosslinked dimers of the p75 neurotrophin receptor."

Journal of cell science
Vol. 122 - 2009;
PubMed ID: 19706676

"The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor."

Genes & development
Vol. 22 - 2008;
PubMed ID: 18334619

"NRAGE, a p75NTR adaptor protein, is required for developmental apoptosis in vivo."

Cell death and differentiation
Vol. 15 - 2008;
PubMed ID: 18772898

"Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures."

The Journal of neuroscience : the official journal of the Society for Neuroscience
Vol. 28 - 2008;
PubMed ID: 18815271

"Downregulation of glutaredoxin but not glutathione loss leads to mitochondrial dysfunction in female mice CNS: implications in excitotoxicity."

Neurochemistry international
Vol. 51 - 2007;
PubMed ID: 17512091

"Down-regulation of glutaredoxin by estrogen receptor antagonist renders female mice susceptible to excitatory amino acid mediated complex I inhibition in CNS."

Brain research
Vol. 1125 - 2006;
PubMed ID: 17109834
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Disclosure or Conflict of Interest

Rajappa S Kenchappa PhD has nothing to disclose

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