Medpedia

Walter J Jessen PhD

Computational Biologist, Covance Biomarker Center of Excellence

Indianapolis, IN

Education

Universities

Texas A&M University

PhD, Molecular Biology/Biochemistry
1998 to 2004

Purdue Univerity

B.S., Physics
1992 to 1998

Postgraduate Training

Cincinnati Children's Hospital

2004 to 2008
Biomedical Informatics

Publications

Articles

"Cyclin D1 is a selective modifier of androgen-dependent signaling and androgen receptor function."

The Journal of biological chemistry
Vol. 286 - 2011;
PubMed ID: 21212260

"Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene."

EMBO molecular medicine
Vol. 1 - 2010;
PubMed ID: 20049725

"Gene expression analysis identifies potential biomarkers of neurofibromatosis type 1 including adrenomedullin."

Clinical cancer research : an official journal of the American Association for Cancer
Vol. 16 - 2010;
PubMed ID: 20739432

"Activator protein-1 transcription factors are associated with progression and recurrence of prostate cancer."

Cancer research
Vol. 68 - 2008;
PubMed ID: 18381418

"Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer."

Genome biology
Vol. 8 - 2008;
PubMed ID: 17615082

"The SWI/SNF ATPase Brm is a gatekeeper of proliferative control in prostate cancer."

Cancer research
Vol. 68 - 2008;
PubMed ID: 19074882

"Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data."

BMC bioinformatics
Vol. 8 - 2007;
PubMed ID: 17683565

"Prolonged exposure to reduced levels of androgen accelerates prostate cancer progression in Nkx3.1; Pten mutant mice."

Cancer research
Vol. 67 - 2007;
PubMed ID: 17909013

"Active PHO5 chromatin encompasses variable numbers of nucleosomes at individual promoters."

Nature structural & molecular biology
Vol. 13 - 2006;
PubMed ID: 16491089

"Mapping chromatin structure in vivo using DNA methyltransferases."

Methods (San Diego, Calif.)
Vol. 33 - 2004;
PubMed ID: 15039089
» Show more

Books

Contemporary Endocrinology: Genomics in Endocrinology

Gene profiling analysis of androgen receptor mediated function.
Humana Press Inc.
New Jersey
2007

DNA Structure, Chromatin and Gene Expression.

Dynamic chromatin remodeling at the budding yeast PHO5 promoter.
Research Signpost
India
2007

Lectures and Presentations

Integrative genomic approaches to identify biomarkers and therapeutic targets in NF1.

2009
Covance, Indianapolis, Indiana.

NF1: Timing and Targets

2008
The 2008 Neurofibromatosis Conference, Cincinnati Children’s Hospital, Cincinnati, Ohio.

Toward a Molecular Model of Disease Progression in Atrial Fibrillation.

2007
The Institute of Molecular Pharmacology and Biophysics, University of Cincinnati College of Medicine, Cincinnati, Ohio.

Bidirectional Propagation of Chromatin Remodeling During Transcriptional Activation in vivo.

2004
Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio.

Disclosure or Conflict of Interest

Walter J Jessen PhD has nothing to disclose

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